Reviews

Impact of mindfulness-based interventions on anxiety and depression among adolescents with a neurological disorder: A systematic narrative review

  • Albany LaGore 1, 2 *
  • Nadine Kridli 2, 3
  • Ron Piscotty 1
  • Suha Kridli 1
  • 1. School of Nursing, Oakland University, Rochester, Michigan, United States
  • 2. C.S. Mott Children’s Hospital, Ann Arbor, Michigan, United States
  • 3. T.H. Chan School of Medicine, University of Massachusetts, Worcester, Massachusetts, United States
* Correspondence:

Abstract

Background: Adolescents with neurological disorders (NDs) experience significantly higher rates of depression, anxiety, or both relative to adolescents in the general population. The purpose of this systematic narrative review was to examine the existing literature evaluating the effects of mindfulness-based interventions (MBIs) on anxiety, depression, or both among adolescents with a known ND.
Methods: Articles published in the English language within the last 10 years were screened. Studies included in this review must have implemented an MBI. 
Results: Ten articles met the inclusion criteria for final analysis. Across the included studies, MBI-based physical and behavioral interventions demonstrated improvements in psychological, emotional, and behavioral outcomes, including reductions in pain, emotional dysregulation, and attentional difficulties. However, findings related to improvements in anxiety and depression were mixed, as several studies did not report statistically significant changes in either outcome.
Conclusions: Future research is needed to clarify the effects of MBIs on adolescents with NDs and comorbid anxiety and/or depression. Future studies should specifically target this population to gain deeper insights into the impact of MBIs on mental health outcomes and overall well-being, with particular attention to anxiety and depression.

Keywords: Anxiety; Depression; Mindfulness; Neurological disease; Psychology; Therapy
Article Info
Published In
Vol. 16, No. 6
2026
Received
Jan 03, 2026
Accepted
Apr 30, 2026
Published
May 25, 2026
How to cite
LaGore A, Kridli N, Piscotty R, Kridli S. Impact of mindfulness-based interventions on anxiety and depression among adolescents with a neurological disorder: A systematic narrative review. Journal of Nursing Education and Practice. 2026;16(6):35-43.

This work is licensed under a Creative Commons Attribution 4.0 License.